Site author Richard Steane
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The BioTopics website gives access to interactive resource material, developed to support the learning and teaching of Biology at a variety of levels.
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6-aminopenicillanic acid
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Spectrum | Narrow | Moderate (amino-penicillins) |
Broad (combination antibiotic) |
Extended (ureidopenicillins and carboxypenicillins) |
Active against | Staphylococci and Streptococci | Staphylococci (sensitive strains only), Haemophilus influenzae, Salmonella, Listeria, and Group A streptococci | bacteria to left, and possibly Klebsiella | bacteria to left, and possibly Pseudomonas spp (Gram negative) |
Examples |
ß-lactamase sensitive
Benzylpenicillin (penicillin G), Phenoxymethylpenicillin (penicillin V) ß-lactamase resistant Methicillin, Cloxacillin, Flucloxacillin, Dicloxacillin |
amoxicillin, ampicillin | co-amoxiclav (amoxicillin plus clavulanic acid, a non-antibiotic compound with a similar structure to penicillin that acts as an inhibitor of penicillinase produced by penicillin-resistant bacterial strands) | azlocillin, mezlocillin , piperacillin, carbenicillin* , ticarcillin*
* likely to be used in conjunction with a penicillinase inhibitor |
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3-aminomonobactamic acid |