The body's defence systems against microbial diseases
First line
- prevention of entry due to physical and chemical barriers;
Skin - generally dry - wounds healed after blood clots
Nasal hairs - trap larger particles
Cilia in the respiratory system act together with mucus to trap smaller particles e.g. bacteria and pass these into the digestive system for disposal by acids and enzymes.
Lysozyme is an enzyme, found in many body fluids e.g. tears, that breaks down cell walls of many bacteria
Second line
- non specific
Phagocytes (white blood cells) detect and engulf any thing "foreign" to the body, e.g. invading bacteria, and digest them
The inflammatory response due to increased blood flow causes swelling and heat and increases contact with white blood cells
Third line
- specific immune system
Antibodies produced by lymphocytes (white blood cells) in response to antigens on the surface of cells of invading micro-organisms.
This topic has connections with other units on this site:-
Blood